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Adverse Events Clinical Questions Addressed

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1. Which AEs are elevated in treatment vs. control? Which AE could be a safety signal?

EG Most Frequent AE EG P-risk Plot EG Hazard Ratios  
Figure11_AE_200.png g_volcano_f_rd_200.png Matange_ForestPlot_Pocock_200.png  
Click here for Most Frequent AE Data Click here for P-risk Plot Data Click here for Hazard Ratios Data    
Comment on Most Frequent AE Comment on P-risk Plot Data Comment on Hazard Ratios  

2. Which AE could be a safety signal?

EG Most Frequent AE EG P-risk Plot  
Figure11_AE_200.png g_volcano_f_rd_200.png  
Click here for Most Frequent AE Data Click here for P-risk Plot Data  
Comment on Most Frequent AE Comment on P-risk Plot Data  

3. Is there a difference in the time to the first event across treatment groups?

EG Time to AE Occurrence    
Cherny_time_event_200.png    
Click here for Time to AE Occurrence Data    
Comment on Time to AE Occurrence    

4. What are the trends of time to the first event among different AEs?

EG Time to AE Occurrence    
Cherny_time_event_200.png    
Click here for Time to AE Occurrence Data    
Comment on Time to AE Occurrence    

5. Which AEs are elevated in patient subgroups?

EG Hazard Ratios    
Matange_ForestPlot_Pocock_200.png    
Click here for Hazard Ratios Data    
Comment on Hazard Ratios    

6. What are the risk factors for an AE?

EG Hazard Ratios    
Matange_ForestPlot_Pocock_200.png    
Click here for Hazard Ratios Data    
Comment on Hazard Ratios    

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Topic revision: r14 - 28 May 2014 - 13:59:23 - MaryBanach
 

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