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Title: Indiana - Design of Genetic Studies

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Title Indiana - Design of Genetic Studies
Contributor/Contact Dan Koller, PhD
Institution Indiana
Acknowledgment Please cite the appropriate contributors/authors/contacts when using or adapting these materials.
Format PDF slides
Attachment Design of Genetic Studies

Type of Course Single Presentation
Level of Course Beginning
Audience Graduate Student
Topics Description Biostatistics Course for Health Care Providers: A Short Course

Objectives of this course are:
1 - Review basic genetic concepts
2 - Review the study designs and statistical methods that led to genetic advances in medicine
3 - Review concepts in genetics which are being widely used in current studies seeking to dissect the genetic contribution to the disease
Software Program



Keywords Molecular markers
Microsatellite markers
Single Nucleotide Polymorphisms (SNPs)
Single gene (Mendelian) disorders
Genetically complex disorders
Twin studies
Familial aggregation
Meiosis and linkage
Genome screen approach
LOD score
Potential candidate approach
Linkage vs association
Linkage Disequilibrium Studies
Association Studies
Population based approach - case control design
Family based approach - Transmission Disequilibrium Test (TDT)
See Also

Type of Activity Course Slides
Disclaimer The views expressed within CTSpedia are those of the author and must not be taken to represent policy or guidance on the behalf of any organization or institution with which the author is affiliated.
Topic revision: r4 - 08 Oct 2012 - 14:41:36 - MaryBanach

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