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Title: Indiana - Study Design

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Title Indiana - Study Design
Contributor/Contact Patrick Monahan, PhD
Institution Indiana
Acknowledgment Please cite the appropriate contributors/authors/contacts when using or adapting these materials.
Format PDF slides
Attachment Study Design
URL_Web_Link

Type of Course Single Presentation
Level of Course Mid-level
Audience Clinical Researcher
Topics Description Biostatistics for Health Care Providers: A Short Course

The objectives of this course are:
* Describe the elements of a research study
* Describe the main observational study designs: Epidemiologic and Outcomes
* Describe estimates of exposure-disease association, including relative, attributable, and population attributable risk and odds ratio
Software Program

Datasets

Data

Keywords Observation
Informal experimentation
Formal experimentation: Evidence based medicine and Causal inference
Elements of a study
Question and Testable Hypothesis
Outcome variable and its measurement
Experimental study design
Population
Protocol
Analyses
Conclusion should answer question
Epidemiologic study designs
Case Series
Assess association between risk factors and disease
Ecologic
Cross-Sectional
Case-Control
Prospective and Historical Perspective
Measures of Disease Frequency
Prevalence
Cumulative Incidence
Incidence Rate
Risk vs Rate
Ecologic Studies
Example of Ecologic Study - Breast Cancer
Advantages and Disadvantages of Ecologic Studies
Cross-Sectional Studies
Example of Cross-Sectional Study - NHANES
Advantages and Disadvantages of Cross-Sectional Studies
Case-Control Studies
Measures of Association - Case-Control: Odds Ratio
2x2 Table
Example of Case-Control Study - Smoking
Example of Case-Control Study - Febrile Seizures
Advantages and Disadvantages of Case-Control Studies
Prospective Studies
Example of Prospective Study - British Male Doctors and Smoking
Measure of Association - Prospective Studies: Relative Risk, Attributable Risk, and Population Attributable Risk
Advantages and Disadvantages of Prospective Studies
Historical Prospective Studies
Example of Historical Prospective Study - Allegheny Steelworkers
Advantages and Disadvantages of Historical Prospective Studies
Case Control vs Cohort Studies
Outcome Studies
Common Outcome Measures: Morbidity, mortality, disease severity (PASI, NYHA), health status (SF-36, SIP), Quality of Life (QWB)
Advantages and Disadvantages of Health Care Delivery Studies
See Also

Type of Activity Course Slides
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Topic revision: r4 - 08 Oct 2012 - 14:45:17 - MaryBanach
 

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