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P-2 Efficacy
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Title Depicting Phase 2 Efficacy Results
Graph_Subgroup General Principles
Code Added Yes
Description Scatterplot of the baseline and end of treatment lesion counts with super-imposed smoothed regression lines. In addition, tabular information is provided near the left-hand side of the graphic to give information about the magnitude of the overall treatment effect.
Contributor/Email Mat Soukup (email: Mat.Soukup@fda.hhs.gov)
Background This is a simulated example where the treatment effect (fewer lesions imply greater health benefit) is to be most pronounced in subjects with a low number of baseline lesions.
Special Considerations

Date Original
Original Date 2007
Modified Date

Use/Suitability Exploration
Software Program R
Software R version 2.10
R-Code - Attachment

R-Code

SAS-Code - Attachment

SAS-Code

Stata-Code - Attachment

Stata-Code

Other Code - Attachment

Other Code

Keywords baseline, end of treatment, regression lines, magnitude of overall treatment effect
OPTIONAL FIELDS

References

Datasets

Data

Attached Data

CATEGORIZATIONS

Classification-Evaluation Efficacy
Classification-Graph Type Scatterplot
Graph_Type Scatterplot
Variable Relationship Continuous versus Continuous
Data Types Continuous
Special Cases

Disclaimer The views expressed within CTSpedia are those of the author and must not be taken to represent policy or guidance on the behalf of any organization or institution with which the author is affiliated.
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Reference Image DepictingPhaseTwo_Referemce_200.jpg
Topic revision: r16 - 27 Jul 2018 - 13:00:56 - MatSoukup
 

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