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EthicsCaseStudyForm edit

Title Journal Editor at odds with the IACUC
Long Title Journal Editor at odds with the IACUC
Contributor/Contact Dale J. Benos, PhD (benos@physiology.uab.edu)
Contributor Details Dale J. Benos, PhD
Chairman of the Department of Physiology and Biophysics
The University of Alabama at Birmingham
CTSA Alabama
Case Study Provided A manuscript was submitted to a journal in a response to a "Special Call for Papers." After it was peer-reviewed and accepted for publication, the handling editor raised a potential animal welfare concern (the three reviewers did not raise the concern in their reviews). The problem that concerned the editor involved an experiment that used cecal ligation in rabbits to induce sepsis. The investigators assessed cumulative mortality out to 10 days. The handling editor argued that mortality is not considered an acceptable experimental end point. According to the editor, an investigator is supposed to use a surrogate end point to identify animals that are terminal, but before they become moribund. The manuscript originated from a laboratory in the United States, and the paper stated that the protocol was done with IACUC approval. What should be done?
Data Acquisition, Management, Sharing and Ownership Topics No Data acquisition_management_sharing and ownership Topics
Mentor and Trainee Responsibilities Topics No mentor and trainee responsibilities topics
Publication Practices and Responsible Authorship Topics No publication practices and responsible authorship topics
Peer Review Topics
The significance of peer review,
Qualities of a good review and reviewer,
Reviewer roles in ensuring RCR,
Editorial responsibilities
Collaborative Science Topics No collaborative science topics
Research Misconduct Topics No research misconduct topics
Conflicts of Interest, Law and Policy Topics No conflicts of interest_law_and policy topics
Human Subjects No human subjects
Citation Benos DJ, Fabres J, Famer J, Gutierrez JP, Hennessy K, Kosek D, Lee JH, Olteanu D, Russell T, Shaikh F, and Wang K. Ethics and scientific publication. Advances in Physiology Education 29: 59-74, 2006.
URL http://advan.physiology.org/cgi/content/full/29/2/59
RCR Keyword Peer Review, Manuscript, Journal, Editor, Reviewer
Other RCR Keywords Animal Treatment
Animal Welfare Concerns
Call for Papers
Euthanized
Experimental End Point;
IACUC Approval
Investigators
Moribund
Mortality
Surrogate End Point
Terminal
Case Difficulty Quick
Type of Case Illustrate point
Source for Topic Areas Du Bois, J., & Dueker, J. (2009). Teaching and Assessing the Responsible Conduct of Research: A Delphi Consensus Panel Report. Journal of Research Administration, 40(1), 49-70.
References

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Topic revision: r2 - 12 Nov 2011 - 16:23:50 - MarkYarborough
 
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