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EthicsCaseStudyForm edit

Title Unauthorized use of human tissues?
Long Title Unauthorized use of human tissues?
Contributor/Contact Dale J. Benos, PhD (benos@physiology.uab.edu)
Contributor Details Dale J. Benos, PhD
Chairman of the Department of Physiology and Biophysics
The University of Alabama at Birmingham
CTSA Alabama
Case Study Provided Case Study: Human Use Concerns
During the review of a manuscript, one reviewer noticed that human cardiac tissue was obtained for microarray analysis from a patient during, according to the authors, a standard catheterization procedure used for diagnosis of a specific cardiac myopathy. The authors also stated in the manuscript that informed consent was obtained, and the entire study was reviewed and approved by their institutionís IRB. However, the reviewer, who was a cardiologist, stated categorically that this procedure is not used for diagnosis; the condition is so well defined that its diagnosis is made by less invasive means. The authorsí institution is in a European country. What should be done?
Data Acquisition, Management, Sharing and Ownership Topics No Data acquisition_management_sharing and ownership Topics
Mentor and Trainee Responsibilities Topics No mentor and trainee responsibilities topics
Publication Practices and Responsible Authorship Topics No publication practices and responsible authorship topics
Peer Review Topics
The significance of peer review,
Qualities of a good review and reviewer,
Reviewer roles in ensuring RCR,
Editorial responsibilities
Collaborative Science Topics No collaborative science topics
Research Misconduct Topics No research misconduct topics
Conflicts of Interest, Law and Policy Topics No conflicts of interest_law_and policy topics
Human Subjects Human subjects research
Citation Benos DJ, Fabres J, Famer J, Gutierrez JP, Hennessy K, Kosek D, Lee JH, Olteanu D, Russell T, Shaikh F, and Wang K. Ethics and scientific publication. Advances in Physiology Education 29: 59-74, 2006.
URL http://advan.physiology.org/cgi/content/full/29/2/59
RCR Keyword Peer Review, Manuscript, Journal, Editor, Reviewer
Other RCR Keywords Cardiac Myopathy
European Institution
Human Cardiac
Human Subjects
Informed Consent
Microarray Analysis
Standard Catheterization Procedure
United States Institution
Case Difficulty Quick
Type of Case Illustrate point
Source for Topic Areas Du Bois, J., & Dueker, J. (2009). Teaching and Assessing the Responsible Conduct of Research: A Delphi Consensus Panel Report. Journal of Research Administration, 40(1), 49-70.


Topic revision: r2 - 11 Nov 2011 - 10:08:46 - MarkYarborough
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