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EthicsCaseStudyForm edit

Title Human Subjects
Long Title Study Recruitment and Consent
Contributor/Contact Daniel T. Lackland, DRPH (lackland@musc.edu)
Contributor Details Daniel T. Lackland, DRPH
Department of Neurosciences
Institute of Human Values in Health Care
Medical University of South Carolina
Case Study Provided An investigator has a project that involves the assessment of physical activity and depression. The intervention arm of the study involves a 2.5 walk daily compared with usual physical activity. The pool of potential participants is quite large, but recruitment for the intervention arm is very poor, and biased as obese subjects are reluctant for the daily walk. To boost participation the PI has implemented incentives including walking shoes and exercise attire provided at different stages of the intervention. Recruitment was improved and proposed sample achieved. The intervention demonstrated a significant effect and was presented in a top tier journal. However after numerous attempts, the results could not be replicated by other investigators due to dropout. After 2 years, the incentives were divulged upsetting numerous investigators who have failed while the original PI was viewed a major hero. NIH, who funded the various studies has organized a special emphasis panel to address the situation.
Data Acquisition, Management, Sharing and Ownership Topics

Mentor and Trainee Responsibilities Topics

Publication Practices and Responsible Authorship Topics

Peer Review Topics

Collaborative Science Topics

Research Misconduct Topics
Significance of misconduct,
Factors that contribute to scientific misconduct
Conflicts of Interest, Law and Policy Topics

Human Subjects


URL https://sctr.musc.edu/
RCR Keyword Research Misconduct, Journal
Other RCR Keywords Incentives; Intervention; Investigator; NIH; Obese subjects; Recruitment
Type of Case

Source for Topic Areas Du Bois, J., & Dueker, J. (2009). Teaching and Assessing the Responsible Conduct of Research: A Delphi Consensus Panel Report. Journal of Research Administration, 40(1), 49-70.


Topic revision: r1 - 04 Jan 2012 - 12:17:48 - DebieSchilling
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