Title | Human Subjects |
Long Title | Study Recruitment and Consent |
Contributor/Contact | Daniel T. Lackland, DRPH (lackland@musc.edu) |
Contributor Details |
Daniel T. Lackland, DRPH Department of Neurosciences Institute of Human Values in Health Care Medical University of South Carolina |
CTSA | MUSC |
Case Study Provided | An investigator has a project that involves the assessment of physical activity and depression. The intervention arm of the study involves a 2.5 walk daily compared with usual physical activity. The pool of potential participants is quite large, but recruitment for the intervention arm is very poor, and biased as obese subjects are reluctant for the daily walk. To boost participation the PI has implemented incentives including walking shoes and exercise attire provided at different stages of the intervention. Recruitment was improved and proposed sample achieved. The intervention demonstrated a significant effect and was presented in a top tier journal. However after numerous attempts, the results could not be replicated by other investigators due to dropout. After 2 years, the incentives were divulged upsetting numerous investigators who have failed while the original PI was viewed a major hero. NIH, who funded the various studies has organized a special emphasis panel to address the situation. |
Data Acquisition, Management, Sharing and Ownership Topics | |
Mentor and Trainee Responsibilities Topics | |
Publication Practices and Responsible Authorship Topics | |
Peer Review Topics | |
Collaborative Science Topics | |
Research Misconduct Topics |
Significance of misconduct, Factors that contribute to scientific misconduct |
Conflicts of Interest, Law and Policy Topics | |
Human Subjects | |
Citation | |
URL | https://sctr.musc.edu/ |
RCR Keyword | Research Misconduct, Journal |
Other RCR Keywords | Incentives; Intervention; Investigator; NIH; Obese subjects; Recruitment |
Type of Case | |
Source for Topic Areas | Du Bois, J., & Dueker, J. (2009). Teaching and Assessing the Responsible Conduct of Research: A Delphi Consensus Panel Report. Journal of Research Administration, 40(1), 49-70. |
References | |
Other |